Michigan State vs Michigan Picks and Prediction for Saturday November 7, 2026

The Michigan State Spartans will be on the road Saturday night for a Big Ten rivalry matchup against the Michigan Wolverines inside Michigan Stadium in Ann Arbor, Michigan. The game is scheduled to kick off at 7:30 PM ET, with coverage available on Peacock. Michigan State comes into Saturday with a 2-6 record overall and an 0-5 mark in Big Ten play, riding a lengthy losing streak following an 18-point road loss to UCLA in its last outing. The Michigan Wolverines return home Saturday with a 5-3 record, having won two of their last three games following a seven-point road victory against Rutgers. Michigan enters Saturday as a 13.5-point home favorite at -575 on the moneyline, while Michigan State is listed at +425. The total for this Big Ten showdown is set at 39.5 points. Stay in the action with our College Football Picks.

Michigan State hunts the upset

Alessio Milivojevic leads the Michigan State offense this season with 1,263 passing yards and seven touchdowns on 121 completions. Jazium Patterson is the top ball carrier on the Michigan State roster with 327 yards and five touchdowns on 76 carries. Cam Edwards has chipped in 304 yards and three scores on 64 carries. Chrishon McCray leads the Michigan State receiving corps with 289 yards and one touchdown on 29 catches. Jayden Savoury has added 271 yards on 29 receptions, while Frederick Moore has chipped in 216 yards and two touchdowns on 20 catches.

Offensively, Michigan State was terrible last week, scoring just 10 points on 156 total yards after converting only two third downs and turning the ball over three times. Defensively, Michigan State was obliterated, allowing 28 points on 443 total yards. Leo Hoffman led the Michigan State offense, completing nine passes for 67 yards. Kayd Coffman completed four passes for 42 yards and one touchdown in the loss.

Michigan tries to win the rivalry game

Bryce Underwood leads the Michigan offense this season with 924 passing yards and five touchdowns on 72 completions, along with 222 rushing yards and two scores on 61 carries. Tommy Carr has completed 49 passes for 503 yards and two touchdowns. Jordan Marshall is the top ball carrier on the Michigan roster with 319 yards and five touchdowns on 86 carries. Savion Hiter has added 314 yards and two scores on 87 carries. JJ Buchanan is the top target in the Michigan offense with 611 yards and five touchdowns on 38 receptions. Andrew Morris has chipped in 375 yards and one touchdown on 40 catches.

Defensively, Michigan did just enough a week ago, allowing 21 points on 249 total yards. Offensively, Michigan was the better team, scoring 28 points on 427 total yards while converting 12 third downs in the victory. Tommy Carr led the Michigan offense, completing 22 passes for 266 yards and one touchdown.

Michigan State vs Michigan Picks and Prediction

Pick: Michigan Wolverines -13.5

Michigan has the home-field advantage and the physicality necessary to find success against Michigan State in this rivalry matchup. The Wolverines should be able to establish their rushing attack and create opportunities through the air against a Spartans defense that could struggle with Michigan's offensive balance. Michigan State has enough talent to remain competitive, but the Spartans will need to avoid turnovers and consistently move the chains to keep pace. Michigan should also have opportunities to create pressure defensively and force Michigan State into difficult third-down situations. Look for the Wolverines to control the line of scrimmage, establish the tempo, and use their home-field advantage to secure a key Big Ten victory.

Total Pick: Under 39.5

This rivalry matchup could turn into a physical battle as both teams look to establish their rushing attacks and control possession. Michigan should find success moving the football on the ground, but sustained drives could limit the number of possessions throughout the game. Michigan State could also struggle to generate consistent scoring opportunities if the Wolverines establish pressure defensively and force the Spartans into obvious passing situations. With both teams familiar with one another, expect defensive adjustments to play a significant role as the game progresses. Look for Michigan to control the tempo and limit explosive plays, keeping the overall scoring low enough for this matchup to finish under the total.

Final Picks: Michigan Wolverines -13.5 and Under 39.5