Indiana Pacers vs Memphis Grizzlies Picks and Prediction for Wednesday November 4, 2026
The Indiana Pacers will be on the road Wednesday night for an interconference matchup against the Memphis Grizzlies inside FedExForum in Memphis, Tennessee. The game is scheduled to begin at 8 PM ET as both teams look to pick up an important early-season victory. Indiana comes into Wednesday night with just two wins through its first eight games played, riding a long losing streak following a four-point loss to Atlanta in its last outing. The Memphis Grizzlies stay home Wednesday with six wins through seven games played after a narrow one-point home loss to New Orleans in overtime last time out. Memphis comes into Wednesday night as a -6.5 favorite and -258 on the money line. Indiana is +212, and the total is set at 230.5. Stay in the action with our NBA Pick
Indiana is desperate for a win
The Indiana Pacers offense is averaging 111.8 points on 47% shooting from the floor this season. Defensively, Indiana has been terrible, allowing 115.6 points per game through eight games played. Pascal Siakam is leading the Indiana offense this season, averaging 21.4 points and 7.4 rebounds per game. Tyrese Haliburton has averaged 21.8 points per game this season, but he has played just four games. Andrew Nembhard is averaging 18.5 points and leads the team, dishing out 7.3 assists.
Defensively, Indiana was mediocre in its last outing, giving up 108 points as Atlanta shot 39% from the floor and 45% from beyond the arc. Offensively, Indiana scored 104 points on 48% shooting. The Pacers lost the rebounding battle by double digits and turned the ball over 19 times in the game. Jay Huff led the Indiana offense with 22 points and eight rebounds on 14 shots.
Key Injury Report for Indiana:
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- Kelly Oubre Jr. (GTD) – Nov 4
- Larry Nance Jr. (Out) – Nov 4
- Obi Toppin (GTD) – Nov 4
- T.J. McConnell (Out) – Nov 9
- Ivica Zubac (GTD) – Nov 9
- Johnny Furphy (Out) – Jan 2
Memphis looks to get back on track
The Memphis Grizzlies offense is carrying them this season, averaging 123 points on 48% shooting. Defensively, Memphis has been strong enough, allowing 110.1 points per game this season, though they gave up 135 points in their lone loss of the year. Ty Jerome is leading the Memphis offense this season, averaging 28.2 points and 5.7 assists per game. Cameron Boozer is second on the team, averaging 17.4 points along with a team-high 10.3 rebounds per contest. Isaiah Stewart and Cedric Coward are both tied for third on the roster, averaging 12.8 points per game this season. Jaylen Wells is the fifth Memphis player in double digits this year, averaging 12.7 points per game.
The Memphis offense was phenomenal in its last outing, pouring in 134 points on 52% shooting and 45% from beyond the arc. Defensively, Memphis was terrible, giving up 135 points, including 11 in overtime, on 48% shooting. The Grizzlies did win the rebounding battle by two but turned the ball over 16 times in the loss. Ty Jerome led the Memphis scoring with 40 points on 22 shots.
Key Injury Report for Memphis:
- Scotty Pippen Jr. (Out) – Nov 4
- Quinten Post (Out) – Nov 4
Indiana Pacers vs Memphis Grizzlies Picks and Prediction
Pick: Memphis Grizzlies -6.5
Memphis has the advantage in this matchup with its athleticism, offensive depth, and ability to create scoring opportunities in transition. The Grizzlies should find success attacking an Indiana defense that can struggle to contain opposing teams around the basket. Pascal Siakam gives the Pacers a reliable offensive option, but Indiana will need consistent production from its supporting cast to keep pace. Memphis should also benefit from its ability to force turnovers and turn defensive stops into easy points. Look for the Grizzlies to establish their tempo early and use their home-court advantage to secure the victory.
Total: Over 230.5
Both teams have the offensive capabilities necessary to turn this matchup into a high-scoring contest. Indiana will look to push the pace and create scoring opportunities before Memphis can establish its half-court defense. The Grizzlies should find success attacking the basket and generating second-chance opportunities through their athleticism and rebounding. Neither team will want to get caught playing from behind, which could lead to an increased number of possessions throughout the game. If Indiana can find success from beyond the arc, both teams should have opportunities to put together lengthy scoring runs. Expect an up-tempo contest with plenty of offensive production.
