Milwaukee Bucks vs Boston Celtics Picks and Prediction for Wednesday November 4, 2026

By: Cameron Ross Published 11/04/2026, 12:30 AM ET

The Milwaukee Bucks will travel to Boston, Massachusetts, Wednesday night for an Eastern Conference matchup against the Boston Celtics inside TD Garden. The game is scheduled to begin at 7:30 PM ET as two familiar conference opponents meet in an important early-season contest. Milwaukee comes into Wednesday night struggling this season with just one win through its first seven games played, having lost four of the last five, including three in a row after a 12-point road loss to Minnesota last time out. The Boston Celtics come into Wednesday 5-2 this season following a 16-point road loss to Houston in their last outing to end a lengthy winning streak. Boston comes into Wednesday a -11.5 favorite and a -514 on the Money line. Milwaukee is a +391 and the total is 223.5. Stay in the action with our NBA Picks.

Milwaukee desperate to turn things aroundΒ 

The Milwaukee Bucks offense has averaged 111.1 points on 43% shooting from the floor this season. Defensively, Milwaukee has struggled immensely, giving up 124.1 points per game this year, and they've allowed 126.75 points per game across their last four losses. Tyler Herro is leading the Milwaukee offense this season, averaging 21.9 points per game. Jaime Jaquez Jr. is second, averaging 16.6 points per game this season. Big man Kel'el Ware is averaging 11.4 points, and he leads the team, pulling in 8.7 rebounds. Ryan Rollins is averaging 11 points and leads the way, dishing out 4.4 assists.

The Milwaukee offense was lackluster last time out, scoring just 100 points on 38% shooting and 31% from beyond the arc. Defensively, Milwaukee struggled, giving up 112 points as Minnesota shot better than 40% from the floor. The Bucks lost the rebounding battle and turned the ball over 17 times in the game. Tyler Herro carried the Milwaukee offense against Minnesota, pouring in a team-high 21 points on 18 shots.

Key Injury Report for Milwaukee:

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Boston looks to get back rolling

The Boston Celtics offense is averaging 115 points on 46% shooting. Defensively, Boston is allowing 109.1 points per game this season. Jayson Tatum is leading the Boston offense this season, averaging 27 points and 7.9 assists per game. Paul George is second on the team, averaging 20.7 points, and he leads the team in rebounding, pulling in six rebounds per contest. Payton Pritchard is third on the team, averaging 13.4 points, and Derrick White is averaging a fourth-best 11.1 points per game.

Offensively, Boston struggled last time out, scoring just 93 points, including only 20 in the fourth quarter, on 39% shooting and 29% from beyond the arc. Defensively, Boston was outmatched, giving up 109 points on 54% shooting. Boston did win the rebounding battle by two but turned the ball over 16 times in the loss. Jayson Tatum did everything for Boston last time out, posting a team-high 19 points, six rebounds, and nine assists on 16 shots.

Key Injury Report for Boston:

  • Jayson Tatum (Rest) - GTD
  • Payton Pritchard (Shoulder) - GTD
  • Devin Carter (Illness) - Out

Milwaukee Bucks vs Boston Celtics Picks and Prediction

Pick: Boston Celtics -11.5

Boston has the advantage in this matchup with its perimeter scoring, defensive versatility, and ability to create offensive opportunities through ball movement. Jaylen Brown should play a major role for the Celtics with his ability to attack the basket and create shots from the perimeter. Milwaukee has the offensive weapons to remain competitive, especially if Giannis Antetokounmpo can establish himself around the rim. However, Boston's ability to spread the floor and generate open three-point opportunities could cause problems for the Bucks. Look for the Celtics to use their home-court advantage and defensive intensity to secure the victory.

Total: Over 223.5

Both teams have the offensive talent necessary to produce a high-scoring contest Wednesday night. Milwaukee will look to attack the paint and create scoring opportunities in transition, while Boston should find success moving the basketball and generating quality perimeter looks. The Celtics have multiple players capable of scoring in bunches, and Milwaukee's ability to get downhill could create plenty of trips to the free-throw line. Neither team will want to give up easy opportunities, but the offensive talent on both sides should create enough scoring chances to keep the scoreboard moving. Expect a competitive matchup with consistent offensive production.

Final Picks: Boston Celtics -11.5 and Over 223.5

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