Denver Broncos vs Carolina Panthers Picks and Prediction for Sunday November 8, 2026

By: Cameron Ross Published 11/07/2026, 01:15 PM ET
Jaguars vs. Broncos prediction

The Denver Broncos will be on the road Sunday afternoon for a matchup against the Carolina Panthers inside Bank of America Stadium in Charlotte, North Carolina. The game is scheduled to kick off at 1 PM ET with coverage on CBS. Denver enters Sunday at 6-2 overall, riding a four-game winning streak following a four-point home victory against Kansas City. Carolina returns home at 3-4, having lost three of its last five games, including two straight following an eight-point road loss to Green Bay. The Broncos are three-point road favorites at -155 on the money line, while Carolina is listed at +130. The total is set at 44.5 points. Stay in the action with our NFL Picks.

Denver looks to keep it rolling

Bo Nix is leading the Denver offense this season with 1,493 passing yards and nine touchdowns on 149 completions, along with 114 rushing yards and two scores on 32 carries. JK Dobbins is the top ball carrier on the Denver roster with 306 yards and three touchdowns on 94 carries. Jonah Coleman has chipped in with 134 yards and two touchdowns on 30 carries. Jaylen Waddle leads Denver with 315 receiving yards and two touchdowns on 29 receptions. Courtland Sutton has added 221 yards and one touchdown on 20 catches, while RJ Harvey has chipped in 217 yards and one touchdown on 25 receptions.

The Denver Broncos got the job done offensively in their last outing, scoring 28 points, including 15 in the fourth quarter, on 294 total yards. Defensively, Denver had some issues, allowing 24 points on 399 total yards but held Kansas City scoreless in the fourth quarter to secure the win. Bo Nix led the Denver offense, completing 20 passes for 222 yards and two touchdowns. Jonah Coleman led the Broncos on the ground with 41 yards and one touchdown on 11 carries, while adding a team-high 63 receiving yards on four catches.

Key Injury Report for Denver:

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  • Kris Abrams-Draine (Out) - Ankle
  • Eyioma Uwazurike (Out) - Shoulder
  • Brandon Jones (Out) - Hamstring
  • Talanoa Hufanga (Questionable) - Ankle
  • Dondrea Tillman (Questionable) - Hip

Carolina looks for their second home win

Bryce Young is leading the Carolina offense this season with 1,921 passing yards and 13 touchdowns on 158 completions, along with 34 rushing yards and one touchdown on 10 carries. Chuba Hubbard is the top ball carrier on the team with 540 yards and five touchdowns on 118 carries. Tetairoa McMillan leads Carolina with 569 receiving yards and two touchdowns on 42 receptions. Jalen Coker has added 364 yards and three touchdowns on 27 catches, while Darren Waller has chipped in 209 yards and three touchdowns on 15 receptions.

Offensively, Carolina struggled last week, scoring just 19 points on 258 total yards after converting only five third downs and turning the ball over twice. Defensively, Carolina was outmatched, allowing 27 points, including 20 in the first half, on 354 total yards. Bryce Young led the Carolina offense, completing 23 passes for 209 yards and one touchdown. Chuba Hubbard led the way out of the backfield with 81 yards and one touchdown on 22 carries. Tetairoa McMillan added a team-high 58 receiving yards on six catches.

Key Injury Report for Carolina:

  • Brady Christensen (IR-R) - Hamstring
  • Damien Lewis (Out) - Knee
  • Will Lee III (Out) - Hamstring
  • Jaelan Phillips (Out) - Hamstring
  • Bobby Okereke (Out) - Foot

Denver Broncos vs. Carolina Panthers Picks and Prediction

Pick: Denver Broncos -3

Denver has the defensive talent and overall roster advantage necessary to control this matchup against Carolina. The Broncos should be able to create pressure on the Panthers' quarterback and force Carolina into difficult passing situations. Denver also has enough offensive weapons to establish its rushing attack and create opportunities through the air against a Panthers defense that could struggle to consistently get off the field. Carolina should have some opportunities on its home field, but the Broncos have more ways to control the game. Look for Denver to rely on its defense and offensive balance to secure the road victory.

Total Pick: Under 44.5

Denver has the defensive personnel necessary to make this a difficult matchup for Carolina's offense. The Broncos should be able to limit explosive plays and force the Panthers into long drives, increasing the chances of mistakes. Carolina will also need to establish its defense early and prevent Denver from creating favorable scoring opportunities. The Broncos should have success moving the football, but their ability to control possession could limit the overall number of drives. Expect Denver's defense to dictate the tempo in a matchup that finishes under the total.

Final Picks: Denver Broncos -3 and Under 44.5

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